Metformin reduced the development of lung tumors in mice by more than 70%. Clinical trials on humans for lung, breast and prostate cancer are being organized.
September 01, 2010|By Thomas H. Maugh II, Los Angeles Times
A growing body of evidence suggests that the widely used diabetes drug metformin can reduce the risk of cancer, researchers said Wednesday.
A study in mice exposed to tobacco carcinogens shows that the drug can reduce the development of lung tumors by more than 70%, and results from a small clinical trial in Japan suggest it can reduce rates of colorectal tumors in humans. The National Cancer Institute is now organizing a clinical trial to test the drug in people who smoke, and other trials are testing it against breast and prostate cancer.
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